Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | intramitochondrial chaperone homologues GroEL and GroES can facilitate the folding of nascent premature mitochondrial isoform pmAspAT in rabbit reticulocyte lysate under conditions where it otherwise would not, GroEL alone inhibits the import into mitochondria, which is reversed by GroES | Rattus norvegicus |
General Stability | Organism |
---|---|
enzyme is stabilized by the intramitochondrial chaperone homologues GroEL and GroES | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | mature mAspAT and premature pmAspAT forms of the isozyme | Rattus norvegicus | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
47000 | - |
x * 47000, premature mitochondrial isozyme pmAspAT, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-aspartate + 2-oxoglutarate | Rattus norvegicus | - |
oxaloacetate + L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
mitochondrial isozyme mAspAT | - |
Renatured (Comment) | Organism |
---|---|
guanidinium hydrochloride denatured premature form pmAspAT cannot refold at 30°C, but refolds rapidly in presence of the intramitochondrial chaperone homologues GroEL and GroES | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-aspartate + 2-oxoglutarate | - |
Rattus norvegicus | oxaloacetate + L-glutamate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 47000, premature mitochondrial isozyme pmAspAT, SDS-PAGE | Rattus norvegicus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Rattus norvegicus | pmAspAT | - |
9.6 |