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Literature summary for 2.6.1.16 extracted from
- Glucosaminephosphate synthase of human liver (1976), Biochim. Biophys. Acta, 422, 241-246.
General Stability
| General Stability | Organism |
|---|---|
| isopropanol, 1%, stabilizes during purification | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| UDP-N-acetylglucosamine | feed-back inhibition | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-glutamine + D-fructose 6-phosphate | Homo sapiens | importance for N-acetylglucosamine synthesis in human liver | L-glutamate + D-glucosamine 6-phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 34.8 | - |
- |
Homo sapiens |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -25°C, 1 month, 15% activity loss, ammonium sulfate precipitated enzyme | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-glutamine + D-fructose 6-phosphate | - |
Homo sapiens | L-glutamate + D-glucosamine 6-phosphate | - |
? | |
| L-glutamine + D-fructose 6-phosphate | importance for N-acetylglucosamine synthesis in human liver | Homo sapiens | L-glutamate + D-glucosamine 6-phosphate | - |
? | |
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