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Literature summary for 2.6.1.16 extracted from

  • Badet-Denisot, M.A.; Leriche, C.; Massiere, F.; Badet, B.
    Nitrogen transfer in E. coli glucosamine-6P synthase. Investigations using substrate and bisubstrate analogs (1995), Bioorg. Med. Chem. Lett., 5, 815-820.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
2-Amino-2-deoxyglucitol 6-phosphate competitive with respect to D-fructose 6-phosphate Escherichia coli
DL-delta-1-pyrroline-5-carboxylate competitive with respect to L-glutamine Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.023
-
DL-delta-1-pyrroline-5-carboxylate
-
Escherichia coli
0.088
-
2-Amino-2-deoxyglucitol 6-phosphate takes into account 2.2% of the open form present in a solution of D-fructose 6-phosphate Escherichia coli