Literature summary for 2.6.1.36 extracted from

Mani Tripathi, S.; Ramachandran, R.
Direct evidence for a glutamate switch necessary for substrate recognition: crystal structures of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv (2006), J. Mol. Biol., 362, 877-886.

Search for more literature for 2.6.1.36

Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Mycobacterium tuberculosis

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.2	-	L-lysine	-	Mycobacterium tuberculosis
2.3	-	2-oxoglutarate	-	Mycobacterium tuberculosis

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
50000	-	SDS-PAGE	Mycobacterium tuberculosis

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	P9WQ77	-	-
Mycobacterium tuberculosis H37Rv	P9WQ77	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Mycobacterium tuberculosis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-lysine + 2-oxoglutarate	-	Mycobacterium tuberculosis	2-aminoadipate 6-semialdehyde + L-glutamate	-	r
L-lysine + 2-oxoglutarate	-	Mycobacterium tuberculosis H37Rv	2-aminoadipate 6-semialdehyde + L-glutamate	-	r

Subunits

Subunits	Comment	Organism
dimer	gel filtration	Mycobacterium tuberculosis

Synonyms

Synonyms	Comment	Organism
LAT	-	Mycobacterium tuberculosis
lysine epsilon-aminotransferase	-	Mycobacterium tuberculosis

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.917	-	L-lysine	-	Mycobacterium tuberculosis
1.43	-	2-oxoglutarate	-	Mycobacterium tuberculosis

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	dependent	Mycobacterium tuberculosis

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)