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Literature summary for 2.6.1.42 extracted from
- Ontogeny and subcellular localization of rat liver mitochondrial branched chain amino-acid aminotransferase (2001), Eur. J. Biochem., 268, 6132-6139.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| RT/PCR of BCATm cDNA | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Rattus norvegicus | 5737 | - |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| nucleus | - |
Rattus norvegicus | 5634 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 41000 | - |
fetal liver nuclei, Western blot analysis | Rattus norvegicus |
| 41200 | - |
predicted from amino acid sequence | Rattus norvegicus |
| 43000 | - |
fetal liver supernatant, Western blot analysis | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-isoleucine + 2-oxoglutarate | Rattus norvegicus | - |
3-methyl-2-oxopentanoate + L-glutamate | - |
r |  |
| L-leucine + 2-oxoglutarate | Rattus norvegicus | - |
4-methyl-2-oxopentanoate + L-glutamate | - |
r | |
| L-valine + 2-oxoglutarate | Rattus norvegicus | - |
3-methyl-2-oxobutanoate + L-glutamate | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood | - |
Rattus norvegicus | - |
| brain | - |
Rattus norvegicus | - |
| heart | - |
Rattus norvegicus | - |
| hepatocyte | - |
Rattus norvegicus | - |
| kidney | - |
Rattus norvegicus | - |
| liver | negligible activity in adult, high activity in fetal liver | Rattus norvegicus | - |
| ovary | - |
Rattus norvegicus | - |
| pancreas | - |
Rattus norvegicus | - |
| placenta | - |
Rattus norvegicus | - |
| skeletal muscle | - |
Rattus norvegicus | - |
| skin | - |
Rattus norvegicus | - |
| stomach | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.65 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-isoleucine + 2-oxoglutarate | - |
Rattus norvegicus | 3-methyl-2-oxopentanoate + L-glutamate | - |
r | |
| L-leucine + 2-oxoglutarate | - |
Rattus norvegicus | 4-methyl-2-oxopentanoate + L-glutamate | - |
r | |
| L-valine + 2-oxoglutarate | - |
Rattus norvegicus | 3-methyl-2-oxobutanoate + L-glutamate | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BcaT | - |
Rattus norvegicus |
| BCATm | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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