Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-hydroxy-4-benzyloxyamine dihydrogen phosphate | NSD 1055, up to 30 mM | Homo sapiens | |
3-hydroxy-4-benzyloxyamine dihydrogen phosphate | NSD 1055, up to 30 mM | Rattus norvegicus | |
carbidopa | MK 486, inhibition is more marked if 2-oxoglutarate is used as amino group acceptor rather than phenylpyruvate, pyridoxal 5'-phosphate protects | Rattus norvegicus | |
additional information | not inhibited by benserazide | Homo sapiens | |
additional information | not inhibited by benserazide | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-(3,4-dihydroxyphenyl)-L-alanine + 2-oxoglutarate | i.e. L-dopa | Homo sapiens | 3-(3,4-dihydroxyphenyl)pyruvate + L-glutamate | i.e. DOPP | ? | |
3-(3,4-dihydroxyphenyl)-L-alanine + 2-oxoglutarate | i.e. L-dopa | Rattus norvegicus | 3-(3,4-dihydroxyphenyl)pyruvate + L-glutamate | i.e. DOPP | ? | |
3-(3,4-dihydroxyphenyl)-L-alanine + 3-phenylpyruvate | i.e. L-dopa | Homo sapiens | 3-(3,4-dihydroxyphenyl)pyruvate + L-phenylalanine | - |
? | |
3-(3,4-dihydroxyphenyl)-L-alanine + 3-phenylpyruvate | i.e. L-dopa | Rattus norvegicus | 3-(3,4-dihydroxyphenyl)pyruvate + L-phenylalanine | - |
? | |
L-tyrosine + 2-oxoglutarate | 8% of activity with L-Dopa | Homo sapiens | 3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate | - |
? | |
L-tyrosine + 2-oxoglutarate | 8% of activity with L-Dopa | Rattus norvegicus | 3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate | - |
? |