Cloned (Comment) | Organism |
---|---|
maltose-binding protein fusion protein expressed in Escherichia coli BL21(DE3) | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
PEG 3350 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-azaphenalene-5-carboxylic acid | BFF-122 | Homo sapiens | |
L-2-aminoadipate | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8N5Z0 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + 2-oxoglutarate | - |
Homo sapiens | kynurenic acid + L-glutamate + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
kynurenine aminotransferase II | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00091 | - |
0.0015 mM or the two enantiomers, pH 8.0, 37°C | Homo sapiens | (S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-azaphenalene-5-carboxylic acid |