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Literature summary for 2.6.1.77 extracted from
- Rhodococcus opacus expresses the xsc gene to utilize taurine as a carbon source or as a nitrogen source but not as a sulfur source (2004), Microbiology, 150, 1859-1867.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | enzyme is induced under nitrogen- and carbon-limited conditions | Rhodococcus opacus | |
| additional information | enzyme is induced under nitrogen- and carbon-limited conditions | Rhodococcus jostii RHA1 |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene cluster tauR-ald-tpa, genetic organization | Rhodococcus jostii RHA1 |
| gene cluster tauR-ald-tpa, genetic organization, DNA and amino acid sequence determination and analysis | Rhodococcus opacus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| soluble | - |
Rhodococcus opacus | - |
- |
| soluble | - |
Rhodococcus jostii RHA1 | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 50000 | - |
x * 50000, SDS-PAGE | Rhodococcus opacus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| taurine + pyruvate | Bilophila wadsworthia | - |
L-alanine + 2-sulfoacetaldehyde | - |
? |  |
| taurine + pyruvate | Rhodococcus jostii RHA1 | enzyme is involved in the desulfonation pathway dissimilating taurine | L-alanine + 2-sulfoacetaldehyde | - |
r | |
| taurine + pyruvate | Rhodococcus opacus | enzyme is involved in the desulfonation pathway dissimilating taurine, overview, homeostatic mechanism | L-alanine + 2-sulfoacetaldehyde | - |
r | |
| taurine + pyruvate | Rhodococcus opacus ISO-5 | enzyme is involved in the desulfonation pathway dissimilating taurine, overview, homeostatic mechanism | L-alanine + 2-sulfoacetaldehyde | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bilophila wadsworthia | Q9APM5 | - |
- |
| Rhodococcus jostii RHA1 | - |
inducible enzyme | - |
| Rhodococcus opacus | Q6JE91 | of the tauR-ald-tpa gene cluster; inducible enzyme | - |
| Rhodococcus opacus ISO-5 | Q6JE91 | of the tauR-ald-tpa gene cluster; inducible enzyme | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partially by ultracentrifugation and anion exchange chromatography | Rhodococcus opacus |
| partially by ultracentrifugation and anion exchange chromatography | Rhodococcus jostii RHA1 |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | cells grow on taurine as sole carbon, sulfur, and nitrogen source, enzyme is induced under nitrogen- and carbon-limited conditions | Rhodococcus jostii RHA1 | - |
| additional information | cells grow on taurine as sole carbon, sulfur, and nitrogen source, enzyme is induced under nitrogen- and carbon-limited conditions, activity overview | Rhodococcus opacus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Rhodococcus opacus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| taurine + pyruvate | - |
Bilophila wadsworthia | L-alanine + 2-sulfoacetaldehyde | - |
? | |
| taurine + pyruvate | i.e. 2-aminoethanesulfonate | Rhodococcus opacus | L-alanine + 2-sulfoacetaldehyde | - |
r | |
| taurine + pyruvate | i.e. 2-aminoethanesulfonate | Rhodococcus jostii RHA1 | L-alanine + 2-sulfoacetaldehyde | - |
r | |
| taurine + pyruvate | enzyme is involved in the desulfonation pathway dissimilating taurine | Rhodococcus jostii RHA1 | L-alanine + 2-sulfoacetaldehyde | - |
r | |
| taurine + pyruvate | enzyme is involved in the desulfonation pathway dissimilating taurine, overview, homeostatic mechanism | Rhodococcus opacus | L-alanine + 2-sulfoacetaldehyde | - |
r | |
| taurine + pyruvate | i.e. 2-aminoethanesulfonate | Rhodococcus opacus ISO-5 | L-alanine + 2-sulfoacetaldehyde | - |
r | |
| taurine + pyruvate | enzyme is involved in the desulfonation pathway dissimilating taurine, overview, homeostatic mechanism | Rhodococcus opacus ISO-5 | L-alanine + 2-sulfoacetaldehyde | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 50000, SDS-PAGE | Rhodococcus opacus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| tPA | - |
Bilophila wadsworthia |
| tPA | - |
Rhodococcus opacus |
| tPA | - |
Rhodococcus jostii RHA1 |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Rhodococcus opacus |
| 37 | - |
assay at | Rhodococcus jostii RHA1 |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
assay at | Rhodococcus opacus |
| 9 | - |
assay at | Rhodococcus jostii RHA1 |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Rhodococcus opacus | |
| pyridoxal 5'-phosphate | - |
Rhodococcus jostii RHA1 | |
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Release 2023.1 (January 2023)
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