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Literature summary for 2.6.1.8 extracted from

  • Roberts, E.
    Studies of transamination (1954), Arch. Biochem. Biophys., 48, 395-401.
    View publication on PubMed
Search for more literature for 2.6.1.8

Inhibitors

Inhibitors Comment Organism Structure
streptomycin weak, with 2,4-diaminoglutarate as substrate Escherichia coli
streptomycin weak, with 2,4-diaminoglutarate as substrate Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-2,5-diaminopentanoate + 2-oxoglutarate Escherichia coli
-
 5-amino-2-oxopentanoate + L-glutamate
-
 ?
L-2,5-diaminopentanoate + 2-oxoglutarate Aspergillus fumigatus
-
 5-amino-2-oxopentanoate + L-glutamate
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus
-
-
-
Escherichia coli
-
-
-
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Mus musculus
partial Escherichia coli
partial Aspergillus fumigatus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,4-diaminoglutarate + 2-oxoglutarate
-
 Mus musculus 4-amino-2-oxobutanoate + L-glutamate
-
 ?
2,4-diaminoglutarate + 2-oxoglutarate
-
 Escherichia coli 4-amino-2-oxobutanoate + L-glutamate
-
 ?
2,4-diaminoglutarate + 2-oxoglutarate
-
 Aspergillus fumigatus 4-amino-2-oxobutanoate + L-glutamate
-
 ?
L-2,5-diaminopentanoate + 2-oxoglutarate
-
 Escherichia coli 5-amino-2-oxopentanoate + L-glutamate
-
 ?
L-2,5-diaminopentanoate + 2-oxoglutarate
-
 Aspergillus fumigatus 5-amino-2-oxopentanoate + L-glutamate
-
 ?
additional information omega-amino monocarboxylic acids, e.g. 5-aminopentanoate 4-aminobutanoate, L-aspartate may be transaminated with 2-oxoglutarate by crude enzyme extracts Mus musculus ?
-
 ?
additional information omega-amino monocarboxylic acids, e.g. 5-aminopentanoate 4-aminobutanoate, L-aspartate may be transaminated with 2-oxoglutarate by crude enzyme extracts Escherichia coli ?
-
 ?
additional information omega-amino monocarboxylic acids, e.g. 5-aminopentanoate 4-aminobutanoate, L-aspartate may be transaminated with 2-oxoglutarate by crude enzyme extracts Aspergillus fumigatus ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Mus musculus
30
-
 assay at Escherichia coli
30
-
 assay at Aspergillus fumigatus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Escherichia coli