Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | product inhibition | Rattus norvegicus | |
AMP | not | Rattus norvegicus | |
beta-D-fructose 2,6-bisphosphate | product inhibition | Rattus norvegicus | |
citrate | not | Rattus norvegicus | |
sn-glycerol 3-phosphate | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus | |
0.05 | - |
beta-D-fructose 6-phosphate | pH 7.5, 30°C, with ATP, in presence of phosphate | Rattus norvegicus | |
0.1 | - |
ATP | pH 7.5, 30°C | Rattus norvegicus | |
0.5 | - |
MgATP2- | pH 7.5, 30°C | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | MgATP2 | Rattus norvegicus | |
phosphate | activation | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate | mechanism | Rattus norvegicus | |
ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate | bifunctional protein: 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase, reverse reaction catalysed by fructose 2,6-bisphosphatase: 3.1.3.46 | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + beta-D-fructose 6-phosphate | - |
Rattus norvegicus | ADP + beta-D-fructose 2,6-bisphosphate | via phosphorylenzyme intermediate | r | |
MgATP2- + beta-D-fructose 6-phosphate | - |
Rattus norvegicus | ? | - |
? | |
additional information | also catalyses the degradation of fructose 2,6-bisphosphate (EC 3.1.3.46) | Rattus norvegicus | ? | - |
? | |
additional information | isotope exchange reaction between ATP and ADP in the absence of fructose 6-phosphate | Rattus norvegicus | ? | - |
? | |
additional information | with discrete catalytic sites | Rattus norvegicus | ? | - |
? | |
additional information | isotope exchange between fructose 6-phosphate and fructose 2,6-bisphosphate in the absence of adenine nucleotides | Rattus norvegicus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Rattus norvegicus |