Inhibitors | Comment | Organism | Structure |
---|---|---|---|
citrate | - |
Rattus norvegicus | |
additional information | phosphorylation by cAMP-dependent protein kinase causes 80% decrease in activity of the liver cells but not of hepatoma cells; phosphorylation by cAMP-dependent protein kinase causes inactivation of liver enzyme | Rattus norvegicus | |
phosphoenolpyruvate | - |
Rattus norvegicus | |
sn-glycerol 3-phosphate | 75% decrease in activity of liver enzyme but not hepatoma cells | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | comparison of Km of hepatoma cells and liver enzyme | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | MgATP2 | Rattus norvegicus | |
phosphate | activation | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + beta-D-fructose 6-phosphate | Rattus norvegicus | responsible for regulation of fructose 2,6-bisphosphate-concentration | ADP + beta-D-fructose 2,6-bisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | phosphorylation by cAMP-dependent protein kinase causes 80% decrease in activity of the liver cells but not of hepatoma cells | Rattus norvegicus |
phosphoprotein | phosphorylation by cAMP-dependent protein kinase causes inactivation of liver enzyme | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatoma cell | resembles muscle enzyme | Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + beta-D-fructose 6-phosphate | - |
Rattus norvegicus | ADP + beta-D-fructose 2,6-bisphosphate | - |
? | |
ATP + beta-D-fructose 6-phosphate | responsible for regulation of fructose 2,6-bisphosphate-concentration | Rattus norvegicus | ADP + beta-D-fructose 2,6-bisphosphate | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.025 | - |
citrate | hepatoma cells | Rattus norvegicus | |
0.035 | - |
citrate | - |
Rattus norvegicus | |
0.12 | - |
phosphoenolpyruvate | hepatoma cells | Rattus norvegicus | |
0.2 | - |
phosphoenolpyruvate | liver | Rattus norvegicus | |
0.2 | - |
citrate | liver | Rattus norvegicus |