Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Rattus norvegicus | 5737 | - |
endoplasmic reticulum | - |
Rattus norvegicus | 5783 | - |
lysosome | - |
Rattus norvegicus | 5764 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
microsome | - |
Rattus norvegicus | - |
- |
mitochondrion | - |
Rattus norvegicus | 5739 | - |
nucleus | - |
Rattus norvegicus | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + dolichol | Rattus norvegicus | enzyme can function in augmenting the steady-state levels of dolichyl phosphate by phosphorylating preexisting dolichol molecules | CDP + dolichyl phosphate | - |
? | |
CTP + dolichol | Rattus norvegicus Sprague-Dawley | enzyme can function in augmenting the steady-state levels of dolichyl phosphate by phosphorylating preexisting dolichol molecules | CDP + dolichyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Rattus norvegicus | - |
Sprague-Dawley | - |
Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.15 | - |
relative specific activity in the soluble fraction | Rattus norvegicus |
0.21 | - |
relative specific activity in the mitochondrial lysosomal fraction | Rattus norvegicus |
0.52 | - |
relative specific activity in the nuclear fraction | Rattus norvegicus |
3.8 | - |
relative specific activity in the microsomal fraction, rough and smooth endoplasmic reticulum are found to have higher specific activities than the Golgi fraction | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + dolichol | pig liver dolichol as substrate, R,S-dolichol-11, dolichol-16, dolichol-19 | Rattus norvegicus | CDP + dolichyl phosphate | - |
? | |
CTP + dolichol | enzyme can function in augmenting the steady-state levels of dolichyl phosphate by phosphorylating preexisting dolichol molecules | Rattus norvegicus | CDP + dolichyl phosphate | - |
? | |
CTP + dolichol | pig liver dolichol as substrate, R,S-dolichol-11, dolichol-16, dolichol-19 | Rattus norvegicus Sprague-Dawley | CDP + dolichyl phosphate | - |
? | |
CTP + dolichol | enzyme can function in augmenting the steady-state levels of dolichyl phosphate by phosphorylating preexisting dolichol molecules | Rattus norvegicus Sprague-Dawley | CDP + dolichyl phosphate | - |
? | |
CTP + ficaprenol | - |
Rattus norvegicus | CDP + ficaprenyl phosphate | - |
? | |
CTP + ficaprenol | - |
Rattus norvegicus Sprague-Dawley | CDP + ficaprenyl phosphate | - |
? | |
CTP + polyprenol | polyprenol-16, alpha-trans-polyprenol-16, polyprenol-19 | Rattus norvegicus | CDP + polyprenyl phosphate | - |
? | |
CTP + polyprenol | polyprenol-16, alpha-trans-polyprenol-16, polyprenol-19 | Rattus norvegicus Sprague-Dawley | CDP + polyprenyl phosphate | - |
? | |
additional information | microsomal enzyme shows a marked preference for saturation of the alpha-isoprene, dolichol-16 and dolichol-19 are 2.5fold more active than the corresponding polyprenols, the enzyme is twice as active against naturally occurring polyprenol-16 (alpha-cis-isoprene) compared to synthetic alpha-trans-polyprenol-16, all-trans-2,3-dihydrosolanesol and solanesol are not substrates | Rattus norvegicus | ? | - |
? | |
additional information | microsomal enzyme shows a marked preference for saturation of the alpha-isoprene, dolichol-16 and dolichol-19 are 2.5fold more active than the corresponding polyprenols, the enzyme is twice as active against naturally occurring polyprenol-16 (alpha-cis-isoprene) compared to synthetic alpha-trans-polyprenol-16, all-trans-2,3-dihydrosolanesol and solanesol are not substrates | Rattus norvegicus Sprague-Dawley | ? | - |
? |