Protein Variants | Comment | Organism |
---|---|---|
D84A | 1% of wild-type activity | Lactobacillus johnsonii |
D84E | 41% of wild-type activity, not inhibited by dGTP and dATP | Lactobacillus johnsonii |
D84N | 5% of wild-type activity | Lactobacillus johnsonii |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dGTP | - |
Lactobacillus johnsonii |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.087 | - |
deoxyguanosine | pH 8.0, 20°C | Lactobacillus johnsonii | |
0.34 | - |
deoxyguanosine | pH 8.0, 20°C, D84N mutant enzyme | Lactobacillus johnsonii | |
0.36 | - |
deoxyguanosine | pH 8.0, 20°C, D84A mutant enzyme | Lactobacillus johnsonii | |
0.55 | - |
deoxyguanosine | pH 8.0, 20°C, D84E mutant enzyme | Lactobacillus johnsonii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lactobacillus johnsonii | Q74HC2 | strain R-26, heterodimeric enzyme, deoxyadenosine kinase/deoxguanosine kinase | - |
Lactobacillus johnsonii NCC 533 | Q74HC2 | strain R-26, heterodimeric enzyme, deoxyadenosine kinase/deoxguanosine kinase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + deoxyguanosine | - |
Lactobacillus johnsonii | ADP + dGMP | - |
? | |
ATP + deoxyguanosine | - |
Lactobacillus johnsonii NCC 533 | ADP + dGMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
deoxyadenosine kinase/deoxyguanosine kinase | abbrevation: dAK/dGK | Lactobacillus johnsonii |