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Literature summary for 2.7.1.134 extracted from
- L-myo-inositol 1,4,5,6-tetrakisphosphate (3-hydroxy)kinase (1988), J. Biol. Chem., 249, 283-292.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| soluble | - |
Mus musculus | - |
- |
| soluble | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 29000 | - |
brain enzyme, gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ammonium sulfate, brain enzyme | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| heart | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| macrophage | bone marrow | Mus musculus | - |
| parotid gland | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
specific activities of various rat tissues | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate | no activity with D-myo-inositol 1,3,4,5-tetrakisphosphate | Mus musculus | ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate | - |
? |  |
| ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate | no activity with D-myo-inositol 1,3,4,5-tetrakisphosphate | Rattus norvegicus | ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate | - |
? | |
| ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate | i.e. L-myo-inositol 1,4,5,6-tetrakisphosphate, phosphorylation site: L-3 or D-1 substitution position | Mus musculus | ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate | - |
? | |
| ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate | i.e. L-myo-inositol 1,4,5,6-tetrakisphosphate, phosphorylation site: L-3 or D-1 substitution position | Rattus norvegicus | ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Mus musculus |
| 37 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
assay at | Mus musculus |
| 7 | - |
assay at | Rattus norvegicus |
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Release 2023.1 (January 2023)
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