Cloned (Comment) | Organism |
---|---|
mph gene for Escherichia coli strain CU1 is identical to that previously reported for mphB from Escherichia coli strain BM 2506 | Escherichia coli |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | mph gene is located on nontransmissible plasmid DNA for Escherichia coli strain CU1 | Escherichia coli | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
macrolide 2'-phosphotransferase type II, similar levels of activity with 14-member ring macrolides or 16-member ring macrolides, strain CU1 or BM 2506 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + clarithromycin | 46-55% activity with respect to oleandomycin for strain CU1, 17% activity with respect to oleandomycin for strain BM 2506 | Escherichia coli | ? | - |
? | |
ATP + erythromycin | 81% activity with respect to oleandomycin for strain CU1, 24% activity with respect to oleandomycin for strain BM 2506 | Escherichia coli | ADP + erythromycin-2'-O-phosphate | - |
? | |
ATP + josamycin | 75-95% activity with respect to oleandomycin for strain CU1, 96% activity with respect to oleandomycin for strain BM 2506 | Escherichia coli | ? | - |
? | |
ATP + kitasamycin | 52% activity with respect to oleandomycin for strain CU1, 61% activity with respect to oleandomycin for strain BM 2506 | Escherichia coli | ? | - |
? | |
ATP + oleandomycin | - |
Escherichia coli | ADP + oleandomycin 2'-O-phosphate | - |
? | |
ATP + roxithromycin | 42% activity with respect to oleandomycin for strain CU1, about 2% activity with respect to oleandomycin for strain BM 2506 | Escherichia coli | ? | - |
? | |
ATP + spiramycin | 57-75% activity with respect to oleandomycin for strain CU1, 26% activity with respect to oleandomycin for strain BM 2506 | Escherichia coli | ADP + spiramycin 2'-O-phosphate | - |
? | |
ATP + troleandomycin | 82% activity with respect to oleandomycin for strain CU1, 105% activity with respect to oleandomycin for strain BM 2506 | Escherichia coli | ? | - |
? | |
ATP + tylosin | 60% activity with respect to oleandomycin for strain CU1, 4% activity with respect to oleandomycin for strain BM 2506 | Escherichia coli | ADP + tylosin 2'-phosphate | - |
? |