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Literature summary for 2.7.1.137 extracted from
- Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (z/l) activities (2001), Diabetes, 50, 1901-1910.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | PI 3-kinase is the first step of the insulin signaling pathway to be impaired by high-fat feeding | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
high fat-fed rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| muscle | skeletal muscle | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1-phosphatidylinositol | - |
Rattus norvegicus | ADP + phosphatidylinositol 3-phosphate | - |
? | |
| additional information | PI 3-kinase is the first step of the insulin signaling pathway to be impaired by high-fat feeding | Rattus norvegicus | ? | - |
? | |
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Release 2023.1 (January 2023)
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