Literature summary for 2.7.1.137 extracted from

Ren, M.; Guan, Q.; Zhong, X.; Gong, B.; Sun, Y.; Xin, W.; Guo, J.; Wang, H.; Gao, L.; Zhao, J.
Phosphatidylinositol 3-kinase/nuclear factor-kappaB signaling pathway is involved in the regulation of IGF-I on Fas-associated death domain-like interleukin-1-converting enzyme-inhibitory protein expression in cultured FRTL thyroid cells (2007), J. Mol. Endocrinol., 38, 619-625.

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Inhibitors

Inhibitors	Comment	Organism	Structure
LY294002	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	IGF-I regulates the expression of FLIP in FRTL cells by activating the PI3K/NF-kB cascade	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
thyroid gland	ATCC CRTL-1486	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	IGF-I regulates the expression of FLIP in FRTL cells by activating the PI3K/NF-kB cascade	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)