Literature summary for 2.7.1.137 extracted from

Maira, S.M.; Stauffer, F.; Brueggen, J.; Furet, P.; Schnell, C.; Fritsch, C.; Brachmann, S.; Chene, P.; De Pover, A.; Schoemaker, K.; Fabbro, D.; Gabriel, D.; Simonen, M.; Murphy, L.; Finan, P.; Sellers, W.; Garcia-Echeverria, C.
Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (2008), Mol. Cancer Ther., 7, 1851-1863.

Inhibitors

Inhibitors	Comment	Organism	Structure
NVP-BEZ235	potency and selectivity for efficient P13K pathway blockade, potent in vivo antitumor activity	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue	Comment	Organism	Textmining
prostate cancer cell line	PC3M	Homo sapiens	-

Synonyms	Comment	Organism
PI3K	-	Homo sapiens

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Release 2023.1 (January 2023)