Literature summary for 2.7.1.148 extracted from

Kalinowska-Tluscik, J.; Miallau, L.; Gabrielsen, M.; Leonard, G.A.; McSweeney, S.M.; Hunter, W.N.
A triclinic crystal form of Escherichia coli 4-diphosphocytidyl-2C-methyl-D-erythritol kinase and reassessment of the quaternary structure (2010), Acta Crystallogr. Sect. F, 66, 237-241.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with ADP, to 2.0 A resolution, and comparison with a monoclinic crystal form of a ternary complex of Escherichia coli 4-diphosphocytidyl-2C-methyl-D-erythritol kinase also with two molecules in the asymmetric unit. The molecular packing is different in the two forms. In the asymmetric unit of the triclinic crystal form the substrate-binding sites are occluded by structural elements of the partner, suggesting that the triclinic dimer is an artefact of the crystal lattice. The surface area of interaction in the triclinic form is almost double that observed in the monoclinic form	Escherichia coli

Crystallization (Comment)

Organism

in complex with ADP, to 2.0 A resolution, and comparison with a monoclinic crystal form of a ternary complex of Escherichia coli 4-diphosphocytidyl-2C-methyl-D-erythritol kinase also with two molecules in the asymmetric unit. The molecular packing is different in the two forms. In the asymmetric unit of the triclinic crystal form the substrate-binding sites are occluded by structural elements of the partner, suggesting that the triclinic dimer is an artefact of the crystal lattice. The surface area of interaction in the triclinic form is almost double that observed in the monoclinic form

Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P62615	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	-	Escherichia coli	ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	-	?

Synonyms

Synonyms	Comment	Organism
IspE	-	Escherichia coli

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Release 2023.1 (January 2023)