Any feedback?
Literature summary for 2.7.1.154 extracted from
- Suppression of the alpha-isoform of class II phosphoinositide 3-kinase gene expression leads to apoptotic cell death (2005), Biochem. Biophys. Res. Commun., 329, 6-10.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| growth factors | addition of serum to growth-factor-deficient medium increases PI3K-C2alpha expression | Homo sapiens | |
| Insulin | - |
Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| suppression of expression of recombinant alpha-isoform of class II PI3K and endogenous enzyme in transfected CHO-R1 cells by expression of antisense constructs or DNA fragmentation leads to apoptotic cells death, overview | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | isozyme PI3K-C2alpha is a crucial survival factor for the cell | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O00443 | class II PI3K, alpha-isoform | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | isozyme PI3K-C2alpha is a crucial survival factor for the cell | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| class II phosphoinositide 3-kinase | - |
Homo sapiens |
| class II PI3K | - |
Homo sapiens |
| PI3K-C2alpha | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
