Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | inhibition of reaction by molar exess of EDTA over Mg2+ | Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required for activity | Saccharomyces cerevisiae | |
additional information | Ca2+ and Zn2+ have no effect on activity | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2'-phospho-[ligated tRNA] + NAD+ | specificity for substrates bearing an internal 2'-phosphate | Saccharomyces cerevisiae | mature tRNA + ADP ribose-1'',2''-phosphate + nicotinamide + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | UMP, SAMP, cAMP, UTP, CTP, GTP, ATP and derivatives of NAD+ like NMN, ADP-ribose, ATP-ribose, NADPH, NADP+, NADH do not support dephosphorylation | Saccharomyces cerevisiae | |
NAD+ | heatstable | Saccharomyces cerevisiae |