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Literature summary for 2.7.1.160 extracted from

  • Spinelli, S.L.; Malik, H.S.; Consaul, S.A.; Phizicky, E.M.
    A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli (1998), Proc. Natl. Acad. Sci. USA, 95, 14136-14141.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.160

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Candida albicans
expression in Escherichia coli as a His-6 fusion Saccharomyces cerevisiae
expression in Escherichia coli as a His-6 fusion, expression in Saccharomyces cerevisiae tpt1 mutant Mus musculus
expression in Escherichia coli as a His-6 fusion, expression in Saccharomyces cerevisiae tpt1 mutant Escherichia coli
expression in Saccharomyces cerevisiae tpt1 mutants Arabidopsis thaliana
expression in Saccharomyces cerevisiae tpt1 mutants Schizosaccharomyces pombe

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Archaeoglobus fulgidus
-
-
-
Candida albicans
-
-
-
Escherichia coli
-
 K12 strain
-
Mus musculus
-
-
-
no activity in Bacillus subtilis
-
-
-
no activity in Haemophilus influenzae
-
-
-
no activity in Helicobacter pylori
-
-
-
no activity in Mycoplasma genitalium
-
-
-
Pseudomonas aeruginosa
-
-
-
Pyrococcus horikoshii
-
-
-
Saccharomyces cerevisiae
-
-
-
Schizosaccharomyces pombe
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partially purified Mus musculus
partially purified Escherichia coli
partially purified Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-phospho-[ligated tRNA] + NAD+
-
 Mus musculus mature tRNA + ADP ribose-1'',2''-phosphate + nicotinamide + H2O
-
 ?
2'-phospho-[ligated tRNA] + NAD+
-
 Escherichia coli mature tRNA + ADP ribose-1'',2''-phosphate + nicotinamide + H2O
-
 ?
2'-phospho-[ligated tRNA] + NAD+
-
 Saccharomyces cerevisiae mature tRNA + ADP ribose-1'',2''-phosphate + nicotinamide + H2O
-
 ?
2'-phospho-[ligated tRNA] + NAD+
-
 Arabidopsis thaliana mature tRNA + ADP ribose-1'',2''-phosphate + nicotinamide + H2O
-
 ?
2'-phospho-[ligated tRNA] + NAD+
-
 Schizosaccharomyces pombe mature tRNA + ADP ribose-1'',2''-phosphate + nicotinamide + H2O
-
 ?
2'-phospho-[ligated tRNA] + NAD+
-
 Candida albicans mature tRNA + ADP ribose-1'',2''-phosphate + nicotinamide + H2O
-
 ?

Synonyms

Synonyms Comment Organism
KptA
-
 Escherichia coli
mTPT1
-
 Mus musculus
mTPT1
-
 Pseudomonas aeruginosa
mTPT1
-
 Archaeoglobus fulgidus
mTPT1
-
 Pyrococcus horikoshii
Tpt1
-
 Saccharomyces cerevisiae
Tpt1
-
 Candida albicans