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Literature summary for 2.7.1.164 extracted from

  • Sherrer, R.L.; Ho, J.M.; Söll, D.
    Divergence of selenocysteine tRNA recognition by archaeal and eukaryotic O-phosphoseryl-tRNASec kinase (2008), Nucleic Acids Res., 36, 1871-1880.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Methanocaldococcus jannaschii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-seryl-tRNASec Methanocaldococcus jannaschii
-
ADP + O-phospho-L-seryl-tRNASec
-
?
ATP + L-seryl-tRNASec Methanocaldococcus jannaschii DSM 2661
-
ADP + O-phospho-L-seryl-tRNASec
-
?

Organism

Organism UniProt Comment Textmining
Methanocaldococcus jannaschii Q58933
-
-
Methanocaldococcus jannaschii DSM 2661 Q58933
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Methanocaldococcus jannaschii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-seryl-tRNASec
-
Methanocaldococcus jannaschii ADP + O-phospho-L-seryl-tRNASec
-
?
ATP + L-seryl-tRNASec
-
Methanocaldococcus jannaschii DSM 2661 ADP + O-phospho-L-seryl-tRNASec
-
?
ATP + L-seryl-tRNASec PSTK distinguishes tRNASec from tRNASer. Unlike eukaryotic PSTK, the archaeal enzyme recognizes the acceptor stem rather than the length and secondary structure of the D-stem. The seryl moiety of L-seryl-tRNASec is not required for enzyme recognition, as PSTK efficiently phosphorylates L-threonyl-tRNASec Methanocaldococcus jannaschii O-phospho-L-seryl-tRNASec + ADP
-
?
ATP + L-seryl-tRNASec PSTK distinguishes tRNASec from tRNASer. Unlike eukaryotic PSTK, the archaeal enzyme recognizes the acceptor stem rather than the length and secondary structure of the D-stem. The seryl moiety of L-seryl-tRNASec is not required for enzyme recognition, as PSTK efficiently phosphorylates L-threonyl-tRNASec Methanocaldococcus jannaschii DSM 2661 O-phospho-L-seryl-tRNASec + ADP
-
?
L-threonyl-tRNASec + ATP
-
Methanocaldococcus jannaschii O-phospho-L-threonyl-tRNASec + ADP
-
?
L-threonyl-tRNASec + ATP
-
Methanocaldococcus jannaschii DSM 2661 O-phospho-L-threonyl-tRNASec + ADP
-
?

Synonyms

Synonyms Comment Organism
PSTK
-
Methanocaldococcus jannaschii