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Literature summary for 2.7.1.189 extracted from

  • Roy, V.; Smith, J.A.; Wang, J.; Stewart, J.E.; Bentley, W.E.; Sintim, H.O.
    Synthetic analogs tailor native AI-2 signaling across bacterial species (2010), J. Am. Chem. Soc., 132, 11141-11150.
    View publication on PubMed
Search for more literature for 2.7.1.189

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Salmonella enterica subsp. enterica serovar Typhimurium
Mg2+ required Escherichia coli
Mg2+ required Vibrio harveyi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Vibrio harveyi
-
 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Salmonella enterica subsp. enterica serovar Typhimurium MET715
-
 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Salmonella enterica subsp. enterica serovar Typhimurium MET708
-
 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Vibrio harveyi BB170
-
 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium MET715
-
 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium MET708
-
 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Vibrio harveyi BB170
-
 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium MET715
-
 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium MET708
-
 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Vibrio harveyi BB170
-
 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxydecane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
 ?
ATP + 1,2-dihydroxydecane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
 ?
ATP + 1,2-dihydroxyheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxyheptane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxyhexane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxyhexane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxynonane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
 ?
ATP + 1,2-dihydroxynonane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
 ?
ATP + 1,2-dihydroxyoctane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
 ?
ATP + 1,2-dihydroxyoctane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
 ?
ATP + 1,2-dihydroxyundecane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
 ?
ATP + 1,2-dihydroxyundecane-3,4-dione Vibrio harveyi
-
 ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
 ?
ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
 ?
ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione Vibrio harveyi
-
 ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
 ?
ATP + 4,5-dihydroxypentane-2,3-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
 ?
ATP + 4,5-dihydroxypentane-2,3-dione Vibrio harveyi
-
 ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
 ?
ATP + autoinducer-2 Salmonella enterica subsp. enterica serovar Typhimurium i.e. AI-2 ADP + phosphorylated autoinducer-2
-
 ?
ATP + autoinducer-2 Escherichia coli i.e. AI-2 ADP + phosphorylated autoinducer-2
-
 ?
ATP + autoinducer-2 Vibrio harveyi i.e. AI-2 ADP + phosphorylated autoinducer-2
-
 ?
additional information Salmonella enterica subsp. enterica serovar Typhimurium no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
 ?
additional information Vibrio harveyi no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
 ?
additional information Salmonella enterica subsp. enterica serovar Typhimurium the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
 ?
additional information Escherichia coli the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
 ?
additional information Vibrio harveyi the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
 ?
additional information Salmonella enterica subsp. enterica serovar Typhimurium MET715 no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
 ?
additional information Salmonella enterica subsp. enterica serovar Typhimurium MET715 the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
 ?
additional information Escherichia coli W3110 / ATCC 27325 the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
 ?
additional information Salmonella enterica subsp. enterica serovar Typhimurium MET708 no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
 ?
additional information Salmonella enterica subsp. enterica serovar Typhimurium MET708 the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
 ?
additional information Vibrio harveyi BB170 no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
 ?
additional information Vibrio harveyi BB170 the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 gene lsrK
-
Escherichia coli W3110 / ATCC 27325
-
 gene lsrK
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
 gene lsrK
-
Salmonella enterica subsp. enterica serovar Typhimurium MET708
-
 gene lsrK
-
Salmonella enterica subsp. enterica serovar Typhimurium MET715
-
 gene lsrK
-
Vibrio harveyi
-
 gene lsrK
-
Vibrio harveyi BB170
-
 gene lsrK
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
 Escherichia coli ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
 Vibrio harveyi ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
 Salmonella enterica subsp. enterica serovar Typhimurium MET715 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
 Escherichia coli W3110 / ATCC 27325 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
 Salmonella enterica subsp. enterica serovar Typhimurium MET708 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
 Vibrio harveyi BB170 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium MET715 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
 Escherichia coli W3110 / ATCC 27325 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium MET708 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
 Vibrio harveyi BB170 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium MET715 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
 Escherichia coli W3110 / ATCC 27325 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium MET708 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
 Vibrio harveyi BB170 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxydecane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
 ?
ATP + 1,2-dihydroxydecane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
 ?
ATP + 1,2-dihydroxydecane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
 ?
ATP + 1,2-dihydroxyheptane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxyheptane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxyheptane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
 ?
ATP + 1,2-dihydroxyhexane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxyhexane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxyhexane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
 ?
ATP + 1,2-dihydroxynonane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
 ?
ATP + 1,2-dihydroxynonane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
 ?
ATP + 1,2-dihydroxynonane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
 ?
ATP + 1,2-dihydroxyoctane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
 ?
ATP + 1,2-dihydroxyoctane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
 ?
ATP + 1,2-dihydroxyoctane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
 ?
ATP + 1,2-dihydroxyundecane-3,4-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
 ?
ATP + 1,2-dihydroxyundecane-3,4-dione
-
 Escherichia coli ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
 ?
ATP + 1,2-dihydroxyundecane-3,4-dione
-
 Vibrio harveyi ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
 ?
ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
 ?
ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione
-
 Escherichia coli ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
 ?
ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione
-
 Vibrio harveyi ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
 ?
ATP + 4,5-dihydroxypentane-2,3-dione
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
 ?
ATP + 4,5-dihydroxypentane-2,3-dione
-
 Escherichia coli ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
 ?
ATP + 4,5-dihydroxypentane-2,3-dione
-
 Vibrio harveyi ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
 ?
ATP + autoinducer-2 i.e. AI-2 Salmonella enterica subsp. enterica serovar Typhimurium ADP + phosphorylated autoinducer-2
-
 ?
ATP + autoinducer-2 i.e. AI-2 Escherichia coli ADP + phosphorylated autoinducer-2
-
 ?
ATP + autoinducer-2 i.e. AI-2 Vibrio harveyi ADP + phosphorylated autoinducer-2
-
 ?
additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Escherichia coli ?
-
 ?
additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Vibrio harveyi ?
-
 ?
additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Escherichia coli ?
-
 ?
additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Vibrio harveyi ?
-
 ?
additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Salmonella enterica subsp. enterica serovar Typhimurium MET715 ?
-
 ?
additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Salmonella enterica subsp. enterica serovar Typhimurium MET715 ?
-
 ?
additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Escherichia coli W3110 / ATCC 27325 ?
-
 ?
additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Escherichia coli W3110 / ATCC 27325 ?
-
 ?
additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Salmonella enterica subsp. enterica serovar Typhimurium MET708 ?
-
 ?
additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Salmonella enterica subsp. enterica serovar Typhimurium MET708 ?
-
 ?
additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Vibrio harveyi BB170 ?
-
 ?
additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Vibrio harveyi BB170 ?
-
 ?

Synonyms

Synonyms Comment Organism
lsrK
-
 Salmonella enterica subsp. enterica serovar Typhimurium
lsrK
-
 Escherichia coli
lsrK
-
 Vibrio harveyi

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Salmonella enterica subsp. enterica serovar Typhimurium
7.4
-
 assay at Escherichia coli
7.4
-
 assay at Vibrio harveyi

General Information

General Information Comment Organism
metabolism the enzyme is involved in quorum sensing, overview Salmonella enterica subsp. enterica serovar Typhimurium
metabolism the enzyme is involved in quorum sensing, overview Escherichia coli
metabolism the enzyme is involved in quorum sensing, overview Vibrio harveyi
physiological function autoinducer-2, AI-2, is activated by the bacterial kinase LsrK and modulate AI-2 specific gene transcription through the transcriptional regulator LsrR. Activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview. In vivo, the critical step that makes AI-2 functional in derepressing the lsr operon is phosphorylation by the kinase LsrK. Active autinducer 2 and its analogues quench the quorum sensing response in multiple bacterial species simultaneously, overview Salmonella enterica subsp. enterica serovar Typhimurium
physiological function autoinducer-2, AI-2, is activated by the bacterial kinase LsrK and modulate AI-2 specific gene transcription through the transcriptional regulator LsrR. Activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview. In vivo, the critical step that makes AI-2 functional in derepressing the lsr operon is phosphorylation by the kinase LsrK. Active autinducer 2 and its analogues quench the quorum sensing response in multiple bacterial species simultaneously, overview Escherichia coli
physiological function autoinducer-2, AI-2, is activated by the bacterial kinase LsrK and modulate AI-2 specific gene transcription through the transcriptional regulator LsrR. Activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview. In vivo, the critical step that makes AI-2 functional in derepressing the lsr operon is phosphorylation by the kinase LsrK. Active autinducer 2 and its analogues quench the quorum sensing response in multiple bacterial species simultaneously, overview Vibrio harveyi