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Literature summary for 2.7.1.19 extracted from

  • Marri, L.; Trost, P.; Pupillo, P.; Sparla, F.
    Reconstitution and properties of the recombinant glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase supramolecular complex of Arabidopsis (2005), Plant Physiol., 139, 1433-1443.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
dithiothreitol reduced form, required for full activity Arabidopsis thaliana
thioredoxin reduced form, regulates activity via reversible reduction Arabidopsis thaliana

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Arabidopsis thaliana

Inhibitors

Inhibitors Comment Organism Structure
additional information oxidizing agents inhibit enzyme activity Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
Arabidopsis thaliana 9507
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
97000
-
isolated enzyme, reduced form, gel filtration Arabidopsis thaliana
110000
-
isolated enzyme, oxidized form, gel filtration Arabidopsis thaliana
640000
-
glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase complex, gel filtration Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + D-ribulose 5-phosphate Arabidopsis thaliana part of the Calvin cycle (reductive pentose phosphate pathway), involved in CO2 fixation in photosynthetic organisms ADP + D-ribulose 1,5-bisphosphate
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-ribulose 5-phosphate
-
Arabidopsis thaliana ADP + D-ribulose 1,5-bisphosphate
-
?
ATP + D-ribulose 5-phosphate part of the Calvin cycle (reductive pentose phosphate pathway), involved in CO2 fixation in photosynthetic organisms Arabidopsis thaliana ADP + D-ribulose 1,5-bisphosphate
-
?

Subunits

Subunits Comment Organism
dimer isolated enzyme Arabidopsis thaliana
multimer glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase complex, native form of enzyme with a molecular weight of 640000 Da Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase glyceraldehyde-3-phosphate dehydrogenase and phosphoribulokinase form a supramolecular complex with the regulatory peptide CP12, both enzyme activities strongly dependent on complex formation Arabidopsis thaliana