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Literature summary for 2.7.1.199 extracted from

  • Plumbridge, J.
    Expression of ptsG, the gene for the major glucose PTS transporter in Escherichia coli, is repressed by Mlc and induced by growth on glucose (1998), Mol. Microbiol., 29, 1053-1063.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[protein]-Npi-phospho-L-histidine + D-glucose[side 1] Escherichia coli
-
[protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[protein]-Npi-phospho-L-histidine + D-glucose[side 1]
-
Escherichia coli [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
?

Synonyms

Synonyms Comment Organism
glucose-specific transporter of the phosphotransferase system
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Escherichia coli
PtsG
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Escherichia coli

Expression

Organism Comment Expression
Escherichia coli expression of the major ptsG transcript is induced by repressed by the Mlc protein down
Escherichia coli the enzyme expression is higher in D-glucose media than in glycerol. A mutation in the mlc gene greatly enhances enzyme expression in a glycerol-grown culture but has no effect on enzyme expression during growth on D-glucose up