Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dipyridamole | at high adenosine levels | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
8-azaadenosine | - |
Rattus norvegicus | |
dipyridamole | at low adenosine levels | Rattus norvegicus | |
Mg2+ | strong inhibition above 1 mM | Rattus norvegicus | |
Mn2+ | strong inhibition above 1 mM | Rattus norvegicus | |
NSC 113939 | - |
Rattus norvegicus | |
NSC 113940 | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00015 | 0.0005 | adenosine | - |
Rattus norvegicus | |
0.0033 | - |
adenosine | in the presence of dipyridamol | Rattus norvegicus | |
0.1 | - |
ATP | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | requirement | Rattus norvegicus | |
Mg2+ | 0.5 mM | Rattus norvegicus | |
Mn2+ | can partially substitute for Mg2+ | Rattus norvegicus | |
Mn2+ | activation | Rattus norvegicus | |
Mn2+ | at 0.5 mM | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
39000 | - |
myocard | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Purification (Comment) | Organism |
---|---|
partial, 80fold purification | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | myocard | Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + adenosine | - |
Rattus norvegicus | ADP + AMP | - |
? | |
CTP + adenosine | less efficient than ATP | Rattus norvegicus | CDP + AMP | - |
? | |
GTP + adenosine | better activity than with ATP | Rattus norvegicus | GDP + AMP | - |
? | |
ITP + adenosine | better activity than with ATP | Rattus norvegicus | IDP + AMP | - |
? | |
UTP + adenosine | less efficient than ATP | Rattus norvegicus | UDP + AMP | - |
? |