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Literature summary for 2.7.1.20 extracted from

  • Sen, B.; Venugopal, V.; Chakraborty, A.; Datta, R.; Dolai, S.; Banerjee, R.; Datta, A.K.
    Amino acid residues of Leishmania donovani cyclophilin key to interaction with its adenosine kinase: biological implications (2007), Biochemistry, 46, 7832-7843.
    View publication on PubMed
Search for more literature for 2.7.1.20

Cloned(Commentary)

Cloned (Comment) Organism
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 Leishmania donovani

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Leishmania donovani cyclophilin (LdCyP) dislocated into the cytoplasm of the stressed cells most likely is responsible for reactivation of the AdK activity. R147 of cyclophilin is the most crucial residue in the LdCyP-AdK interaction ?
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 ?
additional information Leishmania donovani under the condition of cellular stress, the ER-located cyclophilins LdCyP is released into the cytoplasm with concomitant increase both in the specific activity of the cytosol-resident AdK and the uptake of radiolabeled Ado into the cells ?
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 ?

Organism

Organism UniProt Comment Textmining
Leishmania donovani
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-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Leishmania donovani

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cyclophilin (LdCyP) dislocated into the cytoplasm of the stressed cells most likely is responsible for reactivation of the AdK activity. R147 of cyclophilin is the most crucial residue in the LdCyP-AdK interaction Leishmania donovani ?
-
 ?
additional information under the condition of cellular stress, the ER-located cyclophilins LdCyP is released into the cytoplasm with concomitant increase both in the specific activity of the cytosol-resident AdK and the uptake of radiolabeled Ado into the cells Leishmania donovani ?
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 ?

Synonyms

Synonyms Comment Organism
ADK
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 Leishmania donovani