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Literature summary for 2.7.1.20 extracted from

  • Pignataro, G.; Maysami, S.; Studer, F.E.; Wilz, A.; Simon, R.P.; Boison, D.
    Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism (2007), J. Cereb. Blood Flow Metab., 28, 17-23.
    View publication on PubMed

Application

Application Comment Organism
medicine the enzyme is a rational therapeutic target to enhance neuroprotection in ischemia Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
brain low levels of adenosine kinase are essential to maintain adenosine-mediated endogenous neuroprotection and pathologic increases in ADK may render the brain more susceptible to injury Mus musculus
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hippocampus transient downregulation of hippocampal ADK after stroke might be a protective mechanism during maturation hippocampal cell loss Mus musculus
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Synonyms

Synonyms Comment Organism
ADK
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Mus musculus