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Literature summary for 2.7.1.202 extracted from

  • Wen, Z.; Browngardt, C.; Burne, R.
    Characterization of two operons that encode components of fructose-specific enzyme II of the sugar:phosphotransferase system of Streptococcus mutans (2001), FEMS Microbiol. Lett., 205, 337-342.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[protein]-Npi-phospho-L-histidine + D-fructose[side 1] Streptococcus mutans
-
[protein]-L-histidine + D-fructose 1-phosphate[side 2]
-
?
[protein]-Npi-phospho-L-histidine + D-fructose[side 1] Streptococcus mutans UA159
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[protein]-L-histidine + D-fructose 1-phosphate[side 2]
-
?

Organism

Organism UniProt Comment Textmining
Streptococcus mutans
-
-
-
Streptococcus mutans serotype c Q8DWE7 and Q8DWE6 Q8DWE7 encodes domains BC, Q8DWE6 encodes domain A of phosphoenolpyruvate-dependent fructose:phosphotransferase system, respectively
-
Streptococcus mutans serotype c UA159 Q8DWE7 and Q8DWE6 Q8DWE7 encodes domains BC, Q8DWE6 encodes domain A of phosphoenolpyruvate-dependent fructose:phosphotransferase system, respectively
-
Streptococcus mutans UA159
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[protein]-Npi-phospho-L-histidine + D-fructose[side 1]
-
Streptococcus mutans [protein]-L-histidine + D-fructose 1-phosphate[side 2]
-
?
[protein]-Npi-phospho-L-histidine + D-fructose[side 1]
-
Streptococcus mutans UA159 [protein]-L-histidine + D-fructose 1-phosphate[side 2]
-
?

Synonyms

Synonyms Comment Organism
FruC
-
Streptococcus mutans serotype c
fructose permease
-
Streptococcus mutans
fructose-specific enzyme II
-
Streptococcus mutans
FruD
-
Streptococcus mutans serotype c
fruI
-
Streptococcus mutans
IICBAFru
-
Streptococcus mutans
IIFru
-
Streptococcus mutans

Expression

Organism Comment Expression
Streptococcus mutans enzyme expression is inducible by sucrose and fructose up

General Information

General Information Comment Organism
metabolism the inducible fructose permease is also responsible for xylitol transport Streptococcus mutans
physiological function FruCD/inducible fructose permeaseFruI double mutants have roughly 30% of the capacity of the wild-type strain to transport fructose via the phosphoenolpyruvate-dependent sugar:phosphotransferase system Streptococcus mutans serotype c