Protein Variants | Comment | Organism |
---|---|---|
H121N | the mutant has less than 7% kinase activity compared to the wild type enzyme | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | thymidine kinase 1 | Mus musculus | 5829 | - |
mitochondrion | thymidine kinase 2 | Mus musculus | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25000 | - |
2 * 25000, isoform TK1, SDS-PAGE | Mus musculus |
25500 | - |
2 * 25500, isoform TK1, calculated from amino acid sequence | Mus musculus |
60000 | - |
isoform TK1, gel filtration | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + thymidine | - |
Mus musculus | ADP + dTMP | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 25000, isoform TK1, SDS-PAGE | Mus musculus |
homodimer | 2 * 25500, isoform TK1, calculated from amino acid sequence | Mus musculus |
monomer or dimer | isoform TK2 | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
thymidine kinase 1 | - |
Mus musculus |
thymidine kinase 2 | - |
Mus musculus |
TK1 | - |
Mus musculus |
TK2 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | isoform TK2-deficient animal show growth retardation and premature death | Mus musculus |