Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
sitting-drop vapor-diffusion method at 22°C, crystal structures of NRK1 in a binary complex with the reaction product nicotinamide mononucleotide at 1.5 A resolution and in a ternary complex with ADP and tiazofurin at 2.7 A resolution. The active site is located in a groove between the central parallel beta sheet core and the LID and NMP-binding domains | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
D138A | mutation has minor effects on catalysis | Homo sapiens |
D36A | mutation abolishes activity | Homo sapiens |
D56A | mutation abolishes activity | Homo sapiens |
K16A | mutation abolishes activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NWW9 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
nicotinamide riboside kinase | - |
Homo sapiens |
NRK1 | - |
Homo sapiens |