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Literature summary for 2.7.1.23 extracted from

  • Gao, H.; Xu, X.
    The cyanobacterial NAD kinase gene sll1415 is required for photoheterotrophic growth and cellular redox homeostasis in Synechocystis sp. strain PCC 6803 (2012), J. Bacteriol., 194, 218-224.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Synechocystis sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
31000
-
 x * 31000, SDS-PAGE Synechocystis sp.

Organism

Organism UniProt Comment Textmining
Synechocystis sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + NAD+
-
 Synechocystis sp. ADP + NADP+
-
 ?

Subunits

Subunits Comment Organism
? x * 31000, SDS-PAGE Synechocystis sp.

Synonyms

Synonyms Comment Organism
NAD kinase
-
 Synechocystis sp.
NADK
-
 Synechocystis sp.
sll1415
-
 Synechocystis sp.
slr0040
-
 Synechocystis sp.

General Information

General Information Comment Organism
malfunction the reduction of the NADP(H) level in the sll1415 mutant leads to a significant accumulation of glucose-6-phosphate and a loss of photoheterotrophic growth Synechocystis sp.
physiological function the NAD kinase gene sll1415 inhibits the transcription of genes involved in redox homeostasis and exerts stronger effects on methyl viologen tolerance than NAD kinase gene slr0040 Synechocystis sp.