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Literature summary for 2.7.1.26 extracted from

  • Mack, M.; van Loon, A.P.; Hohmann, H.P.
    Regulation of riboflavin biosynthesis in Bacillus subtilis is affected by the activity of the flavokinase/flavin adenine dinucleotide synthetase encoded by ribC (1998), J. Bacteriol., 180, 950-955.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.26

Cloned(Commentary)

Cloned (Comment) Organism
expression of ribC gene in Escherichia coli Bacillus subtilis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34200
-
 gel filtration Bacillus subtilis
36000
-
 1 * 36000, SDS-PAGE Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + riboflavin Bacillus subtilis ribC is essential for growth of Bacillus subtilis. RibC is not directly involved in the riboflavin regulatory system ADP + FMN
-
 ?
ATP + riboflavin Bacillus subtilis 168 ribC is essential for growth of Bacillus subtilis. RibC is not directly involved in the riboflavin regulatory system ADP + FMN
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis P54575 RibC from wild-type strain 1012 and RibC820 from riboflavin-overproducing mitant strain RB52.ribC wild-type gene product has both flavokinase and flavin adenine dinucleotide synthetase activity
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Bacillus subtilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + riboflavin
-
 Bacillus subtilis ADP + FMN
-
 ?
ATP + riboflavin ribC is essential for growth of Bacillus subtilis. RibC is not directly involved in the riboflavin regulatory system Bacillus subtilis ADP + FMN
-
 ?
ATP + riboflavin
-
 Bacillus subtilis 168 ADP + FMN
-
 ?
ATP + riboflavin ribC is essential for growth of Bacillus subtilis. RibC is not directly involved in the riboflavin regulatory system Bacillus subtilis 168 ADP + FMN
-
 ?
additional information ribC wild-type gene product has both flavokinase and flavin adenine dinucleotide synthetase activity Bacillus subtilis ?
-
 ?
additional information ribC wild-type gene product has both flavokinase and flavin adenine dinucleotide synthetase activity Bacillus subtilis 168 ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 36000, SDS-PAGE Bacillus subtilis