Cloned (Comment) | Organism |
---|---|
the TK2141 gene encoding PoK, with a His6-Tag on its N-terminus, is overexpressed in Thermococcus kodakarensis | Thermococcus kodakarensis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-phosphopantoate | substrate inhibition | Thermococcus kodakarensis | |
ATP | substrate inhibition | Thermococcus kodakarensis | |
additional information | feedback inhibition by CoA/acetyl-CoA and product inhibition by 4'-phosphopantothenate are not observed | Thermococcus kodakarensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (R)-4-phosphopantoate + beta-alanine | Thermococcus kodakarensis | the enzyme is involved in coenzyme A biosynthesis in the archaea | AMP + diphosphate + (R)-4'-phosphopantothenate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermococcus kodakarensis | Q5JHF1 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Thermococcus kodakarensis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (R)-4-phosphopantoate + beta-alanine | the enzyme is involved in coenzyme A biosynthesis in the archaea | Thermococcus kodakarensis | AMP + diphosphate + (R)-4'-phosphopantothenate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
4-phosphopantoate | non-competitive | Thermococcus kodakarensis |
PoK | - |
Thermococcus kodakarensis |
TK2141 | - |
Thermococcus kodakarensis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
75 | - |
assay at | Thermococcus kodakarensis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Thermococcus kodakarensis |