Any feedback?
Literature summary for 2.7.1.35 extracted from
- The kinetic mechanism of inhibition of liver pyridoxal kinase with tryptophan metabolites (1981), Biochim. Biophys. Acta, 657, 153-158.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3-hydroxyanthranilic acid | IC50: 0.12 mM | Ovis aries |  |
| 3-hydroxykynurenine | IC50: 0.1 mM | Ovis aries | |
| quinolinic acid | IC50: 0.42 mM | Ovis aries | |
| xanthurenic acid | IC50: 0.36 mM | Ovis aries | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Ovis aries |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Ovis aries | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + pyridoxal | - |
Ovis aries | ADP + pyridoxal 5'-phosphate | - |
? | |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.1 | - |
IC50: 0.1 mM | Ovis aries | 3-hydroxykynurenine | |
| 0.12 | - |
IC50: 0.12 mM | Ovis aries | 3-hydroxyanthranilic acid | |
| 0.36 | - |
IC50: 0.36 mM | Ovis aries | xanthurenic acid | |
| 0.42 | - |
IC50: 0.42 mM | Ovis aries | quinolinic acid | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
