Protein Variants | Comment | Organism |
---|---|---|
S145A | 37% of wild-type activity | Homo sapiens |
S146A | 0.02% of wild-type activity | Homo sapiens |
S201A | 200% of wild-type activity | Homo sapiens |
T243A | 39% of wild-type activity | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.15 | - |
ATP | pH 7.5, 30°C, recombinant S145A mutant mevalonate kinase | Homo sapiens | |
0.253 | - |
mevalonate | pH 7.5, 30°C, recombinant S145A mevalonate kinase | Homo sapiens | |
0.38 | - |
ATP | pH 7.5, 30°C, recombinant T243A mevalonate kinase | Homo sapiens | |
0.41 | - |
ATP | pH 7.5, 30°C, recombinant S146A mevalonate kinase | Homo sapiens | |
0.47 | - |
mevalonate | pH 7.5, 30°C, recombinant T243A mevalonate kinase | Homo sapiens | |
0.51 | - |
mevalonate | pH 7.5, 30°C, recombinant S146A mevalonate kinase | Homo sapiens | |
0.51 | - |
ATP | pH 7.5, 30°C, recombinant S201A mevalonate kinase | Homo sapiens | |
2.5 | - |
mevalonate | pH 7.5, 30°C, recombinant S201A mevalonate kinase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + mevalonate | - |
Homo sapiens | ADP + phosphomevalonate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | - |
Homo sapiens |