Literature summary for 2.7.1.36 extracted from

Wang, L.; Nair, A.K.; Menon, K.M.
Ribonucleic acid binding protein-mediated regulation of luteinizing hormone receptor expression in granulosa cells: relationship to sterol metabolism (2007), Mol. Endocrinol., 21, 2233-2241.

Search for more literature for 2.7.1.36

Inhibitors

Inhibitors	Comment	Organism	Structure
25-hydroxycholesterol	expression of mevalonate kinase is regulated by sterol response element-binding protein-1, which is sensitive to the cllular concentration of 25-hydroxycholesterol. Presence of 25-hydroxycholesterol inhibits mevalonate kinase expression and subsequently its binding to luteinizing hormone receptor mRNA	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	mevalonate kinase is directly involved in regulation of luteinizing hormone receptor expression	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
granulosa cell	cultured granulosa cell	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	mevalonate kinase is directly involved in regulation of luteinizing hormone receptor expression	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)