Activating Compound | Comment | Organism | Structure |
---|---|---|---|
D-fructose 1,6-bisphosphate | - |
Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
S12D | the introduction of S12D mutation mimics the effects of phosphorylation | Homo sapiens |
S12E | the introduction of S12E mutation mimics the effects of phosphorylation | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-Ala | - |
Homo sapiens | |
additional information | phosphorylation at Ser12 interrupts an activating interaction of N-terminal residues (including those at positions 7-10) with the main body of the protein, as a means of inhibiting substrate affinity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphoenolpyruvate | - |
Homo sapiens | ATP + pyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PYK | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Homo sapiens |