Application | Comment | Organism |
---|---|---|
medicine | clinical relevance of the enzyme in the basic defect in sialuria | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
cDNA cloned and sequenced, expressed in Escherichia coli HB101 or INValphaF' | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
79000 | - |
assembles to dimer or hexamer | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y223 | human cell lines promyeolytic leukaemia HL-60, HeLa S3, chronic myelogenous leukaemia K-562, lymphoblastic leukaemia MOLT-4, Burkitt's lymphoma Raji, colorectal adenocarcinoma SW480, lung carcinoma A549 and melanoma G361 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa-S3 cell | - |
Homo sapiens | - |
HL-60 cell | - |
Homo sapiens | - |
K-562 cell | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | UDP-GlcNAc 2-epimerase and ManNAc kinase are parts of one bifunctional enzyme, catalyzes the first 2 steps in N-acetylneuraminic acid biosynthesis | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Homo sapiens |
hexamer | - |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
EC 5.1.3.14/EC 2.7.1.60 | - |
Homo sapiens |
UDP-GlcNAc-epimerase/ManNAc kinase | - |
Homo sapiens |