Cloned (Comment) | Organism |
---|---|
expressed in Sf9 insect cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
A524V | 30% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
A630T | 40% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
A631T | 75% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
A631V | 15% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
A631V | 65% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
C13S | 105% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
C303V | 60% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
C303X | no ManNAc kinase activity | Homo sapiens |
D176V | 85% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
D378Y | 45% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
F528C | 35% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
F537I | 60% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
G576E | 15% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
G708S | 5% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
H132Q | 50% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
I200F | 75% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
I472T | 5% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
I587T | 35% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
M712T | 70% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
N519S | 20% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
R11W | 40% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
R177C | 80% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
V331A | 115% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
V572L | 10% ManNAc kinase activity of the wild type enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography and PD-10 gel column filtration | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + N-acetyl-D-mannosamine | - |
Homo sapiens | ADP + N-acetyl-D-mannosamine 6-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-GlcNAc 2-epimerase/ManNAc kinase | - |
Homo sapiens |