Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | enhances activity | Rattus norvegicus | |
3-Mercaptopropionic acid | enhances activity | Rattus norvegicus | |
cetyltrimethyl ammonium bromide | weak stimulation | Rattus norvegicus | |
Cutsum | stimulates | Rattus norvegicus | |
EDTA | 2 mM, marked stimulation, even in presence of 30 mM Mg2+ | Rattus norvegicus | |
GSH | enhances activity | Rattus norvegicus | |
additional information | activity of the enzyme is dependent on SH groups | Rattus norvegicus | |
sodium deoxycholate | stimulates | Rattus norvegicus | |
sodium taurocholate | weak stimulation | Rattus norvegicus | |
Triton X-100 | stimulates | Rattus norvegicus | |
Tween-20 | weak stimulation | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Rattus norvegicus | |
Cu2+ | 0.25 mM CuCl2, complete inhibition | Rattus norvegicus | |
F- | - |
Rattus norvegicus | |
K+ | - |
Rattus norvegicus | |
Na+ | - |
Rattus norvegicus | |
NaF | 70% inhibition at 1 mM, complete inhibition at 10 mM | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | enzyme is activated by Mn2+ or Mg2+ | Rattus norvegicus | |
Mn2+ | enzyme is activated by Mg2+ or Mn2+ | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Storage Stability | Organism |
---|---|
-20°C, brain homogenate in 0.32 M sucrose, stable for up to 6 d | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol | - |
Rattus norvegicus | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? |