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Literature summary for 2.7.1.67 extracted from

  • Xiong, Z.M.; Kitagawa, K.; Nishiuchi, Y.; Kimura, T.; Inagaki, C.
    Protective effects of Abeta-derived tripeptide, Abeta(32-34), on Abeta(1-42)-induced phosphatidylinositol 4-kinase inhibition and neurotoxicity (2007), Neurosci. Lett., 419, 247-252.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
amyloid beta31-34 fragment of amyloid beta, blocks amyloid beta1-42-induced inhibition of type II phosphatidylinositol 4-kinase activity Homo sapiens
amyloid beta32-34 fragment of amyloid beta, blocks amyloid beta1-42-induced inhibition of type II phosphatidylinositol 4-kinase activity. 50% protection at around 1 nM Homo sapiens
amyloid beta32-35 fragment of amyloid beta, blocks amyloid beta1-42-induced inhibition of type II phosphatidylinositol 4-kinase activity Homo sapiens
additional information amyloid34-32, fragment of amyxloid beta with reversed amino acid sequence, shows no protective effects on the inhibition of type II phosphatidylinositol 4-kinase activity Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
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Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
amyloid beta amino acids 1-42, inhibits type II phosphatidylinositol 4-kinase and enhances glutamate toxicity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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