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Literature summary for 2.7.1.68 extracted from

  • Moritz, A.; De Graan, P.N.E.; Gispen, W.H.; Wirtz, K.W.A.
    Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase (1992), J. Biol. Chem., 267, 7207-7210.
    View publication on PubMed
Search for more literature for 2.7.1.68

Activating Compound

Activating Compound Comment Organism Structure
phosphatidic acid stimulates in a concentration-dependent manner up to 20fold when an equal molar ratio of phosphatidic acid to phosphatidylinositol 4-phosphate is attained Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Bos taurus 16020
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plasma membrane synaptosomal plasma membrane Bos taurus 5886
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate Bos taurus the enzyme may be under control of phosphatidic acid level in membranes ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Bos taurus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 Bos taurus ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate the enzyme may be under control of phosphatidic acid level in membranes Bos taurus ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?