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Literature summary for 2.7.1.74 extracted from
- Deoxycytidine kinase. 3. Kinetics and allosteric regulation of the calf thymus enzyme (1970), J. Biol. Chem., 245, 2285-2294.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dCTP | kinetics; reversible by dTTP; reversible by UDP | Bos taurus |  |
| dTTP | at increased deoxycytidine concentrations | Bos taurus | |
| UDP | - |
Bos taurus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | Mg2+/ATP complex is the reactive species | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thymus | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 2'-deoxycytidine | - |
Bos taurus | ADP + 5'-dCMP | - |
? | |
| dTTP + 2'-deoxycytidine | - |
Bos taurus | dTDP + 2'-deoxy-CMP | - |
? | |
| NTP + deoxycytidine | - |
Bos taurus | NDP + dCMP | - |
? | |
| NTP + deoxyguanosine | - |
Bos taurus | NDP + dGMP | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Bos taurus |
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Release 2023.1 (January 2023)
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