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Literature summary for 2.7.1.78 extracted from
- Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase (2006), RNA, 12, 73-82.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Acetivibrio thermocellus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acetivibrio thermocellus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-agarose chromatography | Acetivibrio thermocellus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 5'-dephospho-DNA | - |
Acetivibrio thermocellus | ADP + 5'-phospho-DNA | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 5' polynucleotide kinase | - |
Acetivibrio thermocellus |
| PNKP | - |
Acetivibrio thermocellus |
| polynucleotide kinase-phosphatase | catalyzes ATP-dependent phosphorylation of 5'-OH termini of DNA or RNA polynucleotides and Ni2+/Mn2+-dependent dephosphorylation of 2',3' cyclic phosphate, 2'-phosphate, and 3'-phosphate ribonucleotides | Acetivibrio thermocellus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Acetivibrio thermocellus | |
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Release 2023.1 (January 2023)
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