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Literature summary for 2.7.1.86 extracted from

  • Stuart, G.R.; Humble, M.M.; Strand, M.K.; Copeland, W.C.
    Transcriptional response to mitochondrial NADH kinase deficiency in Saccharomyces cerevisiae (2009), Mitochondrion, 9, 211-221.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.86

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae YPH925
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + NADH
-
 Saccharomyces cerevisiae ADP + NADPH
-
 ?
ATP + NADH
-
 Saccharomyces cerevisiae YPH925 ADP + NADPH
-
 ?

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction yeast cells lacking the mitochondrial NADH kinase encoded by POS5 display increased sensitivity to hydrogen peroxide, a slow-growth phenotype, reduced mitochondrial function and increased levels of mitochondrial protein oxidation and mitochondrial DNA mutations Saccharomyces cerevisiae