Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.2.3 extracted from

  • Tang, S.J.; Ho, M.Y.; Cho, H.C.; Lin, Y.C.; Sun, G.H.; Chi, K.H.; Wang, Y.S.; Jhou, R.S.; Yang, W.; Sun, K.H.
    Phosphoglycerate kinase 1-overexpressing lung cancer cells reduce cyclooxygenase 2 expression and promote anti-tumor immunity in vivo (2008), Int. J. Cancer, 123, 2840-2848.
    View publication on PubMed

Application

Application Comment Organism
medicine PGK-1 may be an important therapeutic target for pharmacological or gene therapy intervention in non-small cell lung carcinoma Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung cancer cell there is no significant difference in cell proliferation between parental Lewis lung carcinoma (LLC-1) and LLC-1 transduced with PGK-1. Overexpression of PGK-1 in LLC-1 reduces the COX-2 expression, and, in turn, affects prostaglandin E2, cell invasion, angiogenesis, and the immune functions, and finally inhibit the tumor progression Mus musculus
-

Synonyms

Synonyms Comment Organism
PGK-1
-
Mus musculus
phosphoglycerate kinase 1
-
Mus musculus