Cloned (Comment) | Organism |
---|---|
overexpressed as a soluble form in Escherichia coli | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
crystallized at 22°C using PEG 4000 as a precipitant. X-ray diffraction data are collected to 2.2 A resolution using synchrotron radiation. The crystals belong to the tetragonal space group P4(3)2(1)2, with cell parameters of a = b = 97.963, c = 164.312 A, and alpha = beta = gamma = 90°. The symmetric unit contains two molecules of creatine kinase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + creatine | the brain-type cytosolic isoform of creatine kinase, which is found mainly in the brain and retina, is a key enzyme in brain energy metabolism, because high-energy phosphates are transfered through the creatine kinase/phosphocreatine shuttle system | Homo sapiens | ADP + phosphocreatine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BB-CK | brain-type cytosolic isoform of creatine kinase | Homo sapiens |