Application | Comment | Organism |
---|---|---|
medicine | PPK1 exhibits potential as a target for chemotherapy | Klebsiella aerogenes |
medicine | PPK1 exhibits potential as a target for chemotherapy | Pseudomonas aeruginosa |
medicine | PPK1 exhibits potential as a target for chemotherapy | Dictyostelium discoideum |
medicine | PPK1 exhibits potential as a target for chemotherapy | Neisseria meningitidis |
medicine | PPK1 exhibits potential as a target for chemotherapy | Bacillus cereus |
medicine | PPK1 exhibits potential as a target for chemotherapy | Myxococcus xanthus |
medicine | PPK1 exhibits potential as a target for chemotherapy | Helicobacter pylori |
medicine | PPK1 exhibits potential as a target for chemotherapy | Bacillus anthracis |
medicine | PPK1 exhibits potential as a target for chemotherapy | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus anthracis | - |
- |
- |
Bacillus cereus | - |
- |
- |
Dictyostelium discoideum | - |
- |
- |
Escherichia coli | P0A7B1 | - |
- |
Helicobacter pylori | - |
- |
- |
Klebsiella aerogenes | - |
- |
- |
Myxococcus xanthus | - |
- |
- |
Neisseria meningitidis | - |
- |
- |
Pseudomonas aeruginosa | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (phosphate)n | - |
Klebsiella aerogenes | ADP + (phosphate)n+1 | - |
? | |
ATP + (phosphate)n | - |
Pseudomonas aeruginosa | ADP + (phosphate)n+1 | - |
? | |
ATP + (phosphate)n | - |
Dictyostelium discoideum | ADP + (phosphate)n+1 | - |
? | |
ATP + (phosphate)n | - |
Neisseria meningitidis | ADP + (phosphate)n+1 | - |
? | |
ATP + (phosphate)n | - |
Bacillus cereus | ADP + (phosphate)n+1 | - |
? | |
ATP + (phosphate)n | - |
Myxococcus xanthus | ADP + (phosphate)n+1 | - |
? | |
ATP + (phosphate)n | - |
Helicobacter pylori | ADP + (phosphate)n+1 | - |
? | |
ATP + (phosphate)n | - |
Bacillus anthracis | ADP + (phosphate)n+1 | - |
? | |
ATP + (phosphate)n | - |
Escherichia coli | ADP + (phosphate)n+1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
poly P kinase 1 | - |
Klebsiella aerogenes |
poly P kinase 1 | - |
Pseudomonas aeruginosa |
poly P kinase 1 | - |
Dictyostelium discoideum |
poly P kinase 1 | - |
Neisseria meningitidis |
poly P kinase 1 | - |
Bacillus cereus |
poly P kinase 1 | - |
Myxococcus xanthus |
poly P kinase 1 | - |
Helicobacter pylori |
poly P kinase 1 | - |
Bacillus anthracis |
poly P kinase 1 | - |
Escherichia coli |
PPK1 | - |
Klebsiella aerogenes |
PPK1 | - |
Pseudomonas aeruginosa |
PPK1 | - |
Dictyostelium discoideum |
PPK1 | - |
Neisseria meningitidis |
PPK1 | - |
Bacillus cereus |
PPK1 | - |
Myxococcus xanthus |
PPK1 | - |
Helicobacter pylori |
PPK1 | - |
Bacillus anthracis |
PPK1 | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Klebsiella aerogenes | |
ATP | - |
Pseudomonas aeruginosa | |
ATP | - |
Dictyostelium discoideum | |
ATP | - |
Neisseria meningitidis | |
ATP | - |
Bacillus cereus | |
ATP | - |
Myxococcus xanthus | |
ATP | - |
Helicobacter pylori | |
ATP | - |
Bacillus anthracis | |
ATP | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
malfunction | deletion of ppk1 causes loss of virulence for animals | Klebsiella aerogenes |
malfunction | deletion of ppk1 causes loss of virulence for animals | Pseudomonas aeruginosa |
malfunction | deletion of ppk1 causes loss of virulence for animals | Dictyostelium discoideum |
malfunction | deletion of ppk1 causes loss of virulence for animals | Neisseria meningitidis |
malfunction | deletion of ppk1 causes loss of virulence for animals | Bacillus cereus |
malfunction | deletion of ppk1 causes loss of virulence for animals | Myxococcus xanthus |
malfunction | deletion of ppk1 causes loss of virulence for animals | Helicobacter pylori |
malfunction | deletion of ppk1 causes loss of virulence for animals | Bacillus anthracis |
malfunction | deletion of ppk1 causes loss of virulence for animals | Escherichia coli |
physiological function | PPK1 regulates error-prone DNA replication by DNA polymerase IV, leading to adaptive mutation | Escherichia coli |